'''Rotenone''' (CAS number 83-79-4) is a colorless-to-red, odorless solid. In solution it is used as a broad-spectrum
insecticide that works by inhibiting the transport of
electrons in the
respiration pathway. It is commonly used in powdered form to treat parasitic
mites on chickens and other
fowl.
It also kills
fish and is used to eradicate exotic fish from their non-native habitats. It is toxic to
humans and other
mammals. However, it breaks down when exposed to sunlight and has a short lifetime (a week or less) in the environment.
Rotenone is produced by extraction from the roots, seeds, and leaves of certain
tropical legumes.
Rotenone and Parkinson's Disease
Research has shown a correlation between intravenous rotenone and
Parkinson's Disease, in
rats. The study does not suggest that rotenone exposure is responsible for Parkinson's Disease in humans, but is consistent with the belief that chronic exposure to environmental toxins can increase the likelihood of the disease.
External Links
Category:Toxicology
Category:Insecticides